{"id":3554,"date":"2024-06-13T10:17:44","date_gmt":"2024-06-13T08:17:44","guid":{"rendered":"https:\/\/www.ptc.cz\/?p=3554"},"modified":"2024-06-13T10:17:44","modified_gmt":"2024-06-13T08:17:44","slug":"studia-dokazuje-ucinnost-protonovej-liecby-rakoviny-analneho-kanala","status":"publish","type":"post","link":"https:\/\/www.ptc.cz\/sk\/blog\/studia-dokazuje-ucinnost-protonovej-liecby-rakoviny-analneho-kanala\/","title":{"rendered":"\u0160t\u00fadia dokazuje \u00fa\u010dinnos\u0165 prot\u00f3novej lie\u010dby rakoviny an\u00e1lneho kan\u00e1la"},"content":{"rendered":"

T\u00edm lek\u00e1rov Prot\u00f3nov\u00e9ho centra v Prahe \u00faspe\u0161ne publikoval \u0161t\u00fadiu, ktor\u00e1 potvrdzuje \u00fa\u010dinnos\u0165 prot\u00f3novej r\u00e1dioterapie met\u00f3dou ceruzkov\u00e9ho skenovania u pacientov s karcin\u00f3mom an\u00e1lneho kan\u00e1la.<\/p>\n

\n
\n

Text vy\u0161iel vo \u0161vaj\u010diarskom lek\u00e1rskom online \u017eurn\u00e1li Cancers.<\/p>\n

\u0160t\u00fadia sa t\u00fdkala celkom 39 pacientov s diagnostikovan\u00fdm karcin\u00f3mom an\u00e1lneho kan\u00e1la, ktor\u00ed podst\u00fapili lie\u010dbu v pra\u017eskom Protonovom centre v \u010dase od febru\u00e1ra 2014 do augusta 2021.<\/p>\n

Aplikovan\u00fd lie\u010debn\u00fd postup<\/h2>\n

V\u0161etci sledovan\u00ed pacienti podst\u00fapili prot\u00f3nov\u00fa r\u00e1dioterapiu v rozsahu 25 frakci\u00ed a frekvenci\u00ed o\u017earovania ka\u017ed\u00fd v\u0161edn\u00fd de\u0148. Pod\u013ea z\u00e1sad lie\u010debn\u00e9ho protokolu bola t\u00fdmto pacientom tie\u017e predp\u00edsan\u00e1 sprievodn\u00e1 chemoterapia cytostatikami.<\/p>\n

\u00da\u010dinnos\u0165 lie\u010dby bola n\u00e1sledne v pravideln\u00fdch intervaloch overovan\u00e1 fyzik\u00e1lnym vy\u0161etren\u00edm per rectum a vy\u0161etren\u00edm na magnetickej rezonancii.<\/p>\n

Ciele \u0161t\u00fadie<\/h2>\n

Okrem prvotn\u00e9ho cie\u013ea, teda zhodnotenia \u00fa\u010dinnosti prot\u00f3novej lie\u010dby pri diagn\u00f3ze karcin\u00f3mu an\u00e1lneho kan\u00e1la, sa \u0161t\u00fadia zaoberala e\u0161te \u010fal\u0161\u00edm cie\u013eom. T\u00fdm bolo ur\u010denie rizika ak\u00fatnej a chronickej toxicity a vyhodnotenie miery nutnosti vykonania kolost\u00f3mie (v\u00fdvodu \u010dreva) u lie\u010den\u00fdch pacientov.<\/p>\n

V\u00fdsledky \u0161t\u00fadie<\/h2>\n

Lie\u010dba priemerne trvala 35 dn\u00ed a n\u00e1sledn\u00e9 sledovanie potom v priemere 30 mesiacov. V\u0161etk\u00fdch 39 pacientov lie\u010dbu dokon\u010dilo, a z toho 30 (76,9 %) bez nutnosti preru\u0161enia. V \u010dase publikovania \u0161t\u00fadie (za\u010diatok roku 2022) \u017eije 34 pacientov. 5 pacientov zomrelo pred publik\u00e1ciou v\u00fdsledkov, z \u010doho 2 \u00famrtia prim\u00e1rne nes\u00faviseli s lie\u010den\u00fdm ochoren\u00edm.<\/p>\n

    \n
  • 32 lie\u010den\u00fdch \u017eije bez n\u00e1vratu ochorenia<\/li>\n
  • 36 pacientov zaznamenalo kompletn\u00fa regresiu (\u00fastup) ochorenia a 2 pacienti \u010diasto\u010dn\u00fa regresiu<\/li>\n
  • u 2 chor\u00fdch bolo nutn\u00e9 zavies\u0165 kolost\u00f3miu<\/li>\n
  • 2 pacientom bola indikovan\u00e1 z\u00e1chrann\u00e1 resekcia (chirurgick\u00e9 odstr\u00e1nenie tkaniva s n\u00e1dorom)<\/li>\n<\/ul>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    T\u00edm lek\u00e1rov Prot\u00f3nov\u00e9ho centra v Prahe \u00faspe\u0161ne publikoval \u0161t\u00fadiu, ktor\u00e1 potvrdzuje \u00fa\u010dinnos\u0165 prot\u00f3novej r\u00e1dioterapie met\u00f3dou ceruzkov\u00e9ho skenovania u pacientov s karcin\u00f3mom an\u00e1lneho kan\u00e1la. Text vy\u0161iel vo \u0161vaj\u010diarskom lek\u00e1rskom online \u017eurn\u00e1li Cancers. \u0160t\u00fadia sa t\u00fdkala celkom 39 pacientov s diagnostikovan\u00fdm karcin\u00f3mom an\u00e1lneho kan\u00e1la, ktor\u00ed podst\u00fapili lie\u010dbu v pra\u017eskom Protonovom centre v \u010dase od febru\u00e1ra 2014 do augusta 2021. Aplikovan\u00fd lie\u010debn\u00fd postup V\u0161etci…<\/p>\n","protected":false},"author":9,"featured_media":2987,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-3554","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/posts\/3554","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/comments?post=3554"}],"version-history":[{"count":1,"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/posts\/3554\/revisions"}],"predecessor-version":[{"id":3555,"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/posts\/3554\/revisions\/3555"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/media\/2987"}],"wp:attachment":[{"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/media?parent=3554"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/categories?post=3554"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ptc.cz\/sk\/wp-json\/wp\/v2\/tags?post=3554"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}